Tamoxifen
For more information check out: Anastrozole Tamoxifen today!
Q: What is quality of life like while on Tamoxifen?
Need answers from people who have taken the drug. I am about to take this drug for the next 5 years of my life to help battle my breast cancer. Is it worth it?
A: ok, im 18 and my mother is 41 and she has been on the drug for 1 year! i think that it is totally worth taking! the only side effects she has experienced is: headache, bone pain “off and on” and like a tingling sensation that moves around her body randomly! she is glad there is a product out there to continue to help fight this terrible disease! if you dont mind me asking was your cancer estrogen positive and how old are you? good luck with all of your treatments, and god bless you! 
Q: I had breast cancer after the chemo and radiation I took arimadex for 2 years and tamoxifen for 1year?
What do I take if I am allergic to both of them?
A: Talk to your oncologist, and look on www.after-cancer.com for information about different, medically proven products and ways of dealing with side effects.
Good luck – if you are being treated in UK then we are very bad at dealing with side effects here – that was why this website was set up, to say how other countries, particularly France, deal very efficiently and effectively with side effects.
Verite R
Q: My Doc has prescribed Tamoxifen and IUI this coming cycle?
- has anyone been on it,any comments or advise.What is the success rate?
A: No comments, cuz I’ve not been on it. However, you’re probably going to receive violation notices because it appears that you’ve asked the very same question posed as 2 different users, which violates guidelines – don’t cheat or they’ll take away your account.
Q: What happens if you stop taking Tamoxifen (Breast cancer drug) for a week?
Hi all, I am asking this question on behalf of my mother, she had breast cancer, then she had an operation and then radiation so the cancer is all gone (Not sure if that’s worded properly), anyhow, she must take tamoxifen to prevent the recurrence of the cancer.
We live in San Francisco but we are currently in rural Sabah, Malaysia, you can only get a months worth of the drug (30 days) but we have been here for 25 days and will be here for another 9 days. She currently has 5 pills, and you are supposed to take one each day. Is she in danger if she takes them all for the next 5 days and has a 4 day break? Also, how should she take them? One every other day? Every day until runs out? Etc..
(Also, the original plan to deal with this was that my father would come and meet us and bring with him another month’s worth, but he couldn’t make it)
So please help!!!
Thanks a lot,
Chris
A: Nothing bad will happen. Tamoxifen adds estrogen to the body (which is where the link to uterine cancer comes from – that is one of those rare side effects) as it blocks estrogen in the breast. So the standard of care is to take tamoxifen for 5 years to protect the breast from cancer. Some women opt not to take the drug at all. It also is not a drug like birth control pills where you have to adhere to a cycle or your hormones will get all out of whack.
Q: What are the ocular side effects of the medicine tamoxifen?
A: Hope this helps… I put the web site where I got the info fron just incase you wanna go look at it.. Good Luck!
GENERIC NAME: tamoxifen
BRAND NAME: Nolvadex
DRUG CLASS AND MECHANISM: Tamoxifen is an antiestrogen (blocks the effect of estrogen on tissue). The precise mechanism of its action is unknown, but one possible mechanism is that it binds and blocks estrogen receptors on the surface of cells, preventing estrogens from binding and activating the cell. It is used in patients for treating and preventing breast cancer. Controversy currently exists as to which breast cancer patients will benefit from this treatment.
PRESCRIPTION: yes
GENERIC AVAILABLE: no
PREPARATIONS: 10mg oral tablets.
STORAGE: Store in a dry place at 15-30°C (59-86°F).
PRESCRIBED FOR: Tamoxifen is used for the treatment of invasive breast cancer, the most common type of breast cancer, following surgery and/or radiation and for preventing invasive breast cancer in women at high risk for developing it. Tamoxifen also is used for the treatment of women following surgery and radiation for a less common type of breast cancer called ductal carcinoma in situ (DCIS or intraductal carcinoma). Women who have had ductal carcinoma in situ are at high risk for developing invasive breast cancer at a later date, and tamoxifen prevents development of the invasive cancer in almost half of the women during the first five years of treatment. Occasionally, tamoxifen is used to stimulate ovulation.
DOSING: Tamoxifen should be taken at doses specifically directed by the physician. Currently, long term dosing is recommended (in excess of 2 years). Tamoxifen can be taken with food.
DRUG INTERACTIONS: Tamoxifen can cause abnormalities of liver tests and other blood tests, and patients taking it should keep appointments for blood work to monitor for these side effects. Patients should report any suspected side effects immediately, especially bleeding and yellowing of the skin.
SIDE EFFECTS: The most common side effects associated with tamoxifen are: hot flashes, weight gain, abnormal menstrual periods, and nausea.
Q: Has anyone had any reaction to the drug tamoxifen?
I have broken out in a rash on the back of my wrist and around my breast. I’m not sure if it is a reaction to the meds or not. Please tell me what you think. I have also spotted and I’ve gone through menopause already a few years ago.
A: If you are post-menopausal, then tamoxifen is not the drug for you, you would instead be on one of the aromatase inhibitors. Tamoxifen is only to be used for women who are not yet done with menopause since it targets the estrogen that is from the ovaries. Ask your doctor about the aromatase inhibitors.
Q: Is anybody taking Tamoxifen tablets following Breast cancer ?
If so, is it normal to get bad diarrhoea, sickness and pains after taking them ?
Sensible answers only please.
A: My mum was on them but I dont recall her having those problems, have you a cancer care nurse you can talk to, as I would advise that.
Q: Does the intake of Tamoxifen for breast cancer affect our uterus ?
I was suggested a hysterectomy after taking tamoxifen for a year.
A: Here’s the data from the NCI
http://www.cancer.gov/cancertopics/factsheet/therapy/tamoxifen
“Tamoxifen increases the risk of two types of cancer that can develop in the uterus: endometrial cancer, which arises in the lining of the uterus, and uterine sarcoma, which arises in the muscular wall of the uterus. Like all cancers, endometrial cancer and uterine sarcoma are potentially life-threatening. Women who have had a hysterectomy (surgery to remove the uterus) and are taking tamoxifen are not at increased risk for these cancers.
Endometrial Cancer
Studies have found the risk of developing endometrial cancer to be about 2 cases per 1,000 women taking tamoxifen each year compared with 1 case per 1,000 women taking placebo. Most of the endometrial cancers that have occurred in women taking tamoxifen have been found in the early stages, and treatment has usually been effective. However, for some breast cancer patients who developed endometrial cancer while taking tamoxifen, the disease was life-threatening.
Uterine Sarcoma
Studies have found the risk of developing uterine sarcoma to be slightly higher in women taking tamoxifen compared with women taking placebo. However, it was less than 1 case per 1,000 women per year in both groups (1, 2). Research to date indicates that uterine sarcoma is more likely to be diagnosed at later stages than endometrial cancer, and may therefore be harder to control and more
life-threatening than endometrial cancer.
Abnormal vaginal bleeding and lower abdominal (pelvic) pain are symptoms of cancers of the uterus. Women who are taking tamoxifen should talk with their doctor about having regular pelvic examinations and should be checked promptly if they have any abnormal vaginal bleeding or pelvic pain between scheduled exams.”
So, the bottom line is that you may have a risk of ~ one in a thousand that you may develop a uterine malignancy related to the tamoxifen therapy. We would have to do a hysterectomies on 1000 women on Tamoxifen to prevent one uterine cancer. If you are the one in 1000 who would have developed a malignancy, it is worth it. For the other 999 women, it is an unnecessary trauma and expense. I wish we knew which ones needed this done.
Q: due to breast cancer have been taking tamoxifen for the last 2 years, side effects terrible, can i just stop t?
surely i wouldn’t drop down dead would i? hopefully get the all clear in 2-3 years, but in the meantime should i be miserable on these drugs or stop taking them and feel a lot happier in myself? when my times up it’s up, so live longer being unhappy or shorter and be happy with myself?
A: Hello,
Maybe talk with your oncologist and see if there is another drug/hormonal therapy you can take without the same side effects. There is an advantage in survival in taking these medications for five years I believe in receptor-positive patients, but your oncologist knows better for your case.
Best Regards,
John Di Saia MD
Q: my friend is a cancer patient what it is that makes her legs swollen,is it tamoxifen of Angisartan?
this angisartan is for highblood,her doctor gave it to her recently.he change the old medicine cause she is experiencing the same problem,swelling of her legs,.
A: She needs to discuss this with her doctor; swelling might possibly be lymphoedema. Although they doctors say that this appears in the arms, I got it in legs.
More info on www.after-cancer.com – look under Lymphoedema and also massage.
Verite R
Q: How many sp^3 hybridized carbon atoms does tamoxifen possess?
A: Look up the structure (you will probably find it in Wikipedia) and count them.
Q: Does anybody have breast cancer and are taking Tamoxifen 20 ?
I was diagnosed with breast cancer and need the leaflet that comes in the Tamoxifen 20 box does anybody have a spare leaflet i can have.
Please help i really badly need this leaflet and would appreciate your help
A: I don’t know why you need it but can you pop into your local chemist tomorrow. I am sure they will help you. I used to take Tamoxifen but now take Arimidex, so can’t help you.
Q: May the vaginal discharge provoked by taking Tamoxifen, causes yeast infection?
I’m taking Tamoxifen after a mastectomy and I developed yeast infection, for the first time in my life. Can the vaginal discharge that Tamoxifen gives me, causes the yeast infection?
Thank you, Estrella
A: Even though Tamoxifen is an antagonist in breast tissue it acts as partial agonist on the endometrium and has been linked to endometrial cancer in some women. Therefore endometrial changes, including cancer, are among tamoxifen’s side effects.
Tamoxifen is hormonal treatment. You may notice vaginal itching and a bad-smelling discharge while on hormonal therapies. That’s because the lack of estrogen can cause a change in the “environment” of the vagina that makes it more inviting to yeast. This creates an ongoing yeast infection of the vagina and vulva (including all of the areas tucked inside, such as under the hood of the clitoris). The infection produces a white paste or small cottage-cheese-like curds in the vaginal area.
To lower your risk of developing yeast infections, gently rinse out your vagina and vulva on a regular basis with water. Ask your doctor if it’s okay use a little bit of a VERY mild soap (like Dove).
If you have obvious signs of yeast infection or your doctor diagnoses yeast, then you can use a medication that helps get the yeast under control. Some of these anti-yeast creams can be bought over the counter.
Q: Has anyone ever successful used nolvadex(Tamoxifen) to treat puffy nipples?
My nipples are kinda puffy although my chest is hard.I am wondering if anyone have used nolvadex to treat it not caused from steroid abuse.
info i am 20.
My nipples look worse when normal and it looks good after workout/shower.
info
I have used nolvadex many times.But never used it to tread nipples.I am like immune to even the biggest things in the market.
A: No, it won’t.
My neighbour is taking tamoxifen as she had breast cancer. She assures me her nipples haven’t changed since being on the drug.
Side effects can include hot flashes, headaches, fatigue, nausea and/or vomiting.
Men who take tamoxifen may experience headaches, nausea and/or vomiting, skin rash, impotence, or a decrease in sexual interest.
Q: does tamoxifen cause severe joint pain in the feet?
I am having a difficult time walking since I began taking tamoxifen.
A: It must.
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